Enter your email Address

Proteins in blood can detect using cellphone camera

Detecting subtle proteins in blood can save many lives but they are difficult and lavish to do so. Keeping in line a new study, that can detect them simply with the help of a cellphone camera.

University of Pennsylvania have developed a test that uses off-the-shelf components and can detect single proteins with results in a matter of minutes.

Using a standard cellphone camera and a set of strobing LED lights, combined with their lab’s microfluidic droplet generators, the team has developed a system that is a thousand times more sensitive than the standard protein assay.

Issadore’s approach works by measuring one protein at a time, by breaking apart the sample into microdroplets, each of which contain either a single protein or none at all.

His lab’s expertise in microfluidics has produced microchips etched with hundreds of microdroplet generators, all working in parallel.

While an off-the-shelf camera can detect whether a microdroplet contains a fluorescent-marker-bound protein or not, the big challenge was to speed up the process. 

Rather than having a single channel, the researchers flow droplets into hundreds of channels that pass by the camera at the same time and can capture the data fast.

A cellphone camera takes about a hundred images a second, and that’s far too slow to be useful for us to resolve these droplets.

The trick that makes the Issadore team’s approach work was to encode this strobing light with a signal that would allow them to tease apart one microdroplet from its neighbors.

READ MORE:

Author: Hasan Akhter

One thought on “Proteins in blood can detect using cellphone camera

Leave a Reply