CRISPR gene-editing to put an end to heart diseases

Genetics already play a great role in figuring out people’s risk of heart disease. A new biotech startup Verve Therapeutics has come up with an innovative plan to use CRISPR gene-editing technology to put an end to heart diseases.

CRISPR gene-editing to put an end to heart diseasesCRISPR gene-editing includes a process by which genes are cut out of or inserted into a person’s DNA strand. The firm’s plan is to use CRISPR in order to edit genes of adults with a greater genetic risk of heart problems so that they more closely resemble the genes of people with a naturally low risk of such ailments.

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“Poor adherence, costs, side effects, limited access all these challenges have limited the impact existing heart medications like cholesterol-lowering statins have had,” Sekar Kathiresan, Verve’s CEO.

The firm is currently exploring seven various genes that scientists have found leave people with a natural resistance to coronary artery disease. It plans to select one or two genes over the next year in order to initiate clinical trials.

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Verve believes that interesting one gene into a person’s DNA will permanently lower their bad cholesterol and cut down their livelihood of having a heart attack.

“With our therapy, we could change the treatment paradigm for heart disease from chronic care, daily pills, or monthly injections to a one-and-done approach,” Kathiresan asserted.

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Moreover, the Verve Therapeutics soon enough found a major firm to back it up. As per the firm, it had raised $58.5 million in financing, most of which came through GV (Google Ventures), the venture capital arm of Google’s parent company Alphabet.

Author: Hasan Akhter

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